Results 41 to 50 of about 2,034,682 (301)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim +8 more
wiley +1 more source
Globalization impact on consumption and distribution in society
MATEC Web of Conferences, 2018 One of the greatest threats to the capital reproduction globalization is the significant increasing of unemployment. Outsourcing creates workplaces outside the framework of TNCs, but in frames of the national economy. From our point of view this is a way
Panfilova Olga +2 more
doaj +1 more source
How does consumer behaviour change? Examples from energy conservation [PDF]
, 2009 A global consumer society is rapidly overshooting ecological limits, there is a dire need to find new ways to change consumer behaviour. Yet history knows few succesful examples of reducing consumption. However, since the 1970s, there is a long legacy of
Heiskanen, Eva +3 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Changes in the Consumption Environment and the Spread of Liquid Consumption:
Maketingu Janaru, 2020 It is very important to consider brand strategy in the digital society from a broader perspective. However, in order to do so, it is necessary to first accurately recognize how the consumption environment changes due to digitization.
Yukihiko Kubota
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Work, consumption and subjectivity in postwar France: Moulinex and the meanings of domestic appliances, 1950s-1970s [PDF]
, 2012 This article responds to some of the limitations of the historiography of consumption in contemporary Europe, notably its tendency to divorce consumer culture from production and to subscribe, in some cases at least, to a rather schematic model of ...
Clarke, J.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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NEW TRENDS IN CONSUMPTION IN CONTEMPORARY SOCIETY. SOCIOLOGICAL REFLECTION
Rozprawy Społeczne, 2019 The aim of the article is to characterize the most common tendencies that occur in consumption in contemporary society, which is part of the research area of consumption sociology.
Olga Filipiak
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source