Results 161 to 170 of about 2,299,030 (376)
Objective The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) in glucocorticoid (GC)‐dependent polymyalgia rheumatica (PMR). TCZ reduced GC use and disease activity at 24 weeks. This study aimed to assess relapse rates after stopping TCZ in patients achieving remission at week 24.
Baptiste Chevet+24 more
wiley +1 more source
Mucosal‐associated invariant T cells in rheumatic diseases.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek+7 more
wiley +1 more source
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit+13 more
wiley +1 more source
Topological contact dynamics II: topological automorphisms, contact homeomorphisms, and non-smooth contact dynamical systems [PDF]
This sequel to our previous paper [MS11b] continues the study of topological contact dynamics and applications to contact dynamics and topological dynamics. We provide further evidence that the topological automorphism groups of a contact structure and a contact form are the appropriate transformation groups of contact dynamical systems.
arxiv
Contact allergy is unlikely to mimic basal cell carcinoma [PDF]
Fiona Chapman+3 more
openalex +1 more source
Abstract Qualitative research is increasingly engaged in anatomical sciences education research. However, many in the discipline are not formally trained in qualitative methodology and—like other research methods—qualitative methods are continually developed and enhanced.
Angelique N. Dueñas+2 more
wiley +1 more source
Immediate contact allergy from hydrolyzed wheat in a cosmetic cream [PDF]
E. Varjonen+2 more
openalex +1 more source
Aims To develop an evidence‐ and consensus‐based patient prioritization tool for use by UK mental health inpatient pharmacy teams. Methods A modified‐Delphi technique was used to obtain experts' agreement on the content, design and practical use of the patient prioritization tool.
Fatima Q. Alshaikhmubarak+3 more
wiley +1 more source
Methylisothiazolinone and Methylchloroisothiazolinone New Insights [PDF]
Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high
Ana Rita Rodrigues-Barata+1 more
doaj