Results 181 to 190 of about 2,299,030 (376)

Rheumatoid arthritis, gold therapy, contact allergy and blood cytokines [PDF]

open access: gold, 2002
Åke Svensson   +7 more
openalex   +1 more source

Improved C5‐Amide Bioisosteres for Human Neuraminidase 1 Inhibitors Based on 2‐Deoxy‐2,3‐Didehydro‐N‐Acetyl Neuraminic Acid

open access: yesChemMedChem, EarlyView.
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Mostafa Radwan   +2 more
wiley   +1 more source

Magnetic Response of Paramagnetic Metal–Organic Frameworks Under an External Magnetic Field and Its Application for Sorption Quantification

open access: yesChemistry–Methods, EarlyView.
Strong external magnetic fields can keep paramagnetic porous particles static without falling down while immersed in a liquid medium, and the strength of the required magnetic field, controlled indirectly by the distance to a permanent magnet, correlates with the mass of adsorbate captured, giving rise to a new technique for quantifying adsorption ...
Rubén Pérez‐Aguirre   +5 more
wiley   +1 more source

Oral contact stomatitis related to toothpaste use: A report of 15 cases

open access: yesJEADV Clinical Practice
Oral contact dermatitis is an inflammatory reaction that is not common in patients but can be caused using certain toothpastes. As a result, patients experience pain, ulceration, erythema, burning sensation, vesicles and so on.
M. Vinant   +5 more
doaj   +1 more source

The impact of coarsening an exposure on partial identifiability in instrumental variable settings [PDF]

open access: yesarXiv
In instrumental variable (IV) settings, such as in imperfect randomized trials and observational studies with Mendelian randomization, one may encounter a continuous exposure, the causal effect of which is not of true interest. Instead, scientific interest may lie in a coarsened version of this exposure.
arxiv  

Pharmacokinetics, Bioequivalence, and Safety Studies of Crisaborole Ointment in Healthy Chinese Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract The aim of this study was to evaluate the bioequivalence and safety of a single application of crisaborole ointment to test formulation and reference formulation in healthy subjects under fasting conditions. A total of 32 subjects were included and divided into 2 groups (test‐reference; reference‐test).
Yanchao Wang   +9 more
wiley   +1 more source

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