Results 51 to 60 of about 126,759 (296)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The dynamical stability of W Ursae Majoris-type systems

, 2008
Theoretical study indicates that a contact binary system would merge into a rapidly rotating single star due to tidal instability when the spin angular momentum of the system is more than a third of its orbital angular momentum.
Albayrak, Barone, Djurasevic, Eaton, Eggleton, Eggleton, Fenghui Zhang, Gazeas, Gurol, Hrivnak, Hut, Kaluzny, Kaluzny, Li, Li, Lifang Li, Lu, Maceroni, Mateo, Mateo, Ozdemir, Qian, Rasio, Rasio, Rucinski, Rucinski, Rucinski, Vaiana, Vilhu, Yakut, Yan, Yang, Zhang   +32 more
core   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Twin Binaries: Studies of Stability, Mass Transfer, and Coalescence

, 2011
Motivated by suggestions that binaries with almost equal-mass components ("twins") play an important role in the formation of double neutron stars and may be rather abundant among binaries, we study the stability of synchronized close and contact ...
Belczynski, Bethe, Chandrasekhar, Chandrasekhar, D'souza, Dan, Eggleton, F. A. Rasio, Habets, Hachisu, Hillwig, Hillwig, Hut, J. C. Lombardi, Jacoby, K. Gearity, K. L. Dooley, Krumholz, Lee, Motl, Nice, Paczyiński, Pinsonneault, Pols, Rasio, Rasio, Santander-Garcia, Stairs, Thorsett, V. Kalogera, W. Holtzman, Wang, Webbink, Weisberg, Willems, Willems, Wong   +36 more
core   +1 more source

Tomographic Separation of Composite Spectra. IX. The Massive Close Binary HD 115071 [PDF]

, 2002
We present the first orbital elements for the massive close binary, HD 115071, a double-lined spectroscopic binary in a circular orbit with a period of 2.73135 +/- 0.00003 days.
C. Lloyd, Claret A., Cruz-Gonzalez C., D. J. Stickland, de Loore C., Douglas R. Gies, Harries T. J., Hilditch R. W., Howarth I. D., John H. Wise, Laura R. Penny, Lorenz R., Meurs E. J. A., Meynet G., Mochnacki S. W., Schaller G., Stickland D. J., Wade R. A.   +17 more
core   +2 more sources

BSN: Photometric Light Curve Analysis of Two Contact Binary Systems LS Del and V997 Cyg [PDF]

Research in Astronomy and Astrophysics
The light curve analyses and orbital period variations for two contact binary stars, LS Del and V997 Cyg, are presented in this work which was conducted in the frame of the Binary Systems of South and North project.
A. Poro, M. Tanrıver, E. Sarvari, Shayan Zavvarei, Hossein Azarara, Laurent Corp, S. Baudart, Asma Ababafi, Nazanin Kahali Poor, Fariba Zare, Ahmet Bulut, Ahmet Keskin   +11 more
semanticscholar   +1 more source

Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank, Benjamin M. Jacobs, Jonathan Bestwick, Ruth Dobson   +3 more
wiley   +1 more source

Detailed Analysis of Six Contact Binaries and their Possible Origin

The Astronomical Journal
A photometric investigation of six binary systems of the W Ursae Majoris (W UMa)-type is presented. We extracted primary and secondary minima from the Transiting Exoplanet Survey Satellite observations of these systems.
Somayeh Soomandar, Lorne Nelson, Joshua Aiken   +2 more
doaj   +1 more source

Can low metallicity binaries avoid merging?

, 2007
Rapid mass transfer in a binary system can drive the accreting star out of thermal equilibrium, causing it to expand. This can lead to a contact system, strong mass loss from the system and possibly merging of the two stars.
Cottaar, M., de Mink, S. E., Pols, O. R.
core   +1 more source