Results 171 to 180 of about 1,929,926 (305)

Efficacy and Safety of Abatacept Versus Placebo During Peanut Oral Immunotherapy for Adults With Severe Peanut Allergy

Allergy, EarlyView.
In this Phase 2a trial, severely peanut‐allergic participants were randomized to abatacept versus placebo with peanut oral immunotherapy (OIT) for 24 weeks, followed by 12 weeks of OIT alone. No significant difference was observed for the primary efficacy outcome (the relative change from baseline in peanut‐specific/total IgE ratio at 24 weeks), but ...
Marie‐Lee Simard, Camille Braun, Éloise Antony, Émilie Roy, Marie‐Ève Gingras, François Graham, Anne Des Roches, Louis Paradis, Kathryn Samaan, Florence Gingras‐Lessard, Roxane Labrosse, Thomas Eiwegger, Philippe Bégin   +12 more
wiley   +1 more source

Occupational Contact Dermatitis in Italy: Bridging the Gap Between Estimated Incidence and Official Reporting Data. [PDF]

J Clin Med
Scilli S, Modenese A.
europepmc   +1 more source

An Extended Transcriptomic Landscape of Human Skin Mast Cells: Unveiling Lineage‐Specific Noncoding RNA Dynamics in FcεRI Activation

Allergy, EarlyView.
FcεRI cross‐linking triggers widespread transcriptional reprogramming in human skin mast cells (> 5000 genes, > 6400 promoters, and 48 novel mast cell‐enriched lncRNAs). Breast skin and foreskin mast cells share core transcriptional programs but differ selectively in tryptase isoenzymes and IL‐8/IL‐1RA release.
Gürkan Bal, Kristin Franke, Stefan Frischbutter, Shiva Raj Tripathi, Kayoko Yasuzawa, Jordan A. Ramilowski, Michihira Tagami, Takeya Kasukawa, Michiel de Hoon, Jay W. Shin, Piero Carninci, Torsten Zuberbier, Magda Babina   +12 more
wiley   +1 more source

Comparing contact dermatitis due to tissue adhesives in port-site closure. [PDF]

Surg Endosc
Holihan JL, Wrather AG, Lancaster C, Bajwa KS, Felinski MM, Shah SK, Stulberg JJ, Wilson TD, Wilson EB.   +8 more
europepmc   +1 more source

Corticosteroid Exposure in Autoimmune Hepatitis: Early Toxicity, Cumulative Burden and Associations With Long‐Term Patient‐Reported Outcomes

Alimentary Pharmacology &Therapeutics, EarlyView.
In a patient‐reported cohort of 565 adults with autoimmune hepatitis, 96.6% reported corticosteroid‐related side effects within 6 months and long‐term toxicity increased with cumulative exposure. The findings support earlier tapering, toxicity monitoring, lower induction dosing when appropriate and selective budesonide use in carefully chosen non ...
Elizabeth Gentry, Mackenzie Woods, Kelsey Green, Nadia Blessing, Craig Lammert   +4 more
wiley   +1 more source

The Alleviative Effect of Oral Administration of <i>Lactiplantibacillus plantarum</i> 22A-3 on Allergic Contact Dermatitis in Mice. [PDF]

Nutrients
Minato KI, Chikazawa M, Unno K, Yamana Y, Tagawa T, Kuwahara H, Mizuno M.   +6 more
europepmc   +1 more source

Contact dermatitis.

Nagoya journal of medical science, 2000
openaire   +2 more sources

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Occupational Allergic Contact Dermatitis Caused by Cyclohexyl Diethanolamine in a Metalworking Fluid. [PDF]

Contact Dermatitis
Pesonen M, Suomela S, Suuronen K.
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source