Results 141 to 150 of about 3,412,277 (344)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Modeling of contact interaction and wear of the trolleybus contact insert-wire tribopair
Проблеми трибологіїThe article presents the results of numerical modeling of the contact interaction of the tribopair "contact insert - contact wire" of a trolleybus using the Ansys software environment.
K.E. Holenko, O.S Kovtun, O.V. Dykha
doaj +1 more source
A Protein Interaction Domain Contacts RNA in the Prespliceosome [PDF]
, 2004 Brenton R. Graveley
openalex +1 more source
, 2019 High-precision HERA data corresponding to a luminosity of around1 fb−1 have been used in the framework of eeqq contactinteractions (CI) to set limits on possible high-energy contributionsbeyond the Standard Model to electron--quark scattering. Measurementsof the inclusive deep inelastic cross sections in neutral and chargedcurrent ep scattering were ...
openaire +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Numerical investigation of hyperelastic solids with contact interaction
Учёные записки Казанского университета: Серия Физико-математические науки, 2018 The paper is devoted to the construction of a computational algorithm for the investigation of hyperelastic solids with the contact interaction. In the framework of the previously developed algorithm for the investigation of large deformations of three ...
A.I. Abdrakhmanova, L.U. Sultanov
doaj
Universal relations for disordered systems
New Journal of PhysicsThe universal relations for spin- $1/2$ fermions with contact interaction in the presence of quenched disorder are discussed. The disorder is modeled by a random external potential with the Gaussian distribution and δ -like two-point correlation function.
V Pastukhov
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