Results 81 to 90 of about 3,412,277 (344)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Contact Interaction Searches at the Linear Collider: Energy, Luminosity and Positron Polarization Dependencies [PDF]
, 2003 Many types of new physics can lead to contact interaction-like modifications in $e^+e^-$ processes below direct production threshold. This report summarizes a survey of contact interaction search reaches at the Linear Collider as functions of energy ...
Rizzo, Thomas G.
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Charmed mesons with a symmetry-preserving contact interaction
, 2017 A symmetry-preserving treatment of a vector-vector contact interaction is used to study charmed heavy-light mesons. The contact interaction is a representation of nonperturbative kernels used in Dyson-Schwinger and Bethe-Salpeter equations of QCD.
El-Bennich, Bruno +2 more
core +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
DEFORMATION MECHANISM OF STRUCTURAL BODY COMPRESSION
Наука и техника, 2018 In order to prepare soil for sowing of agricultural crops it is necessary to have a number of engineering structures that ensure its qualitative treatment and protection from erosion.
О. N. Protasenya +2 more
doaj +1 more source
Third-order particle-hole ring diagrams with contact-interactions and one-pion exchange
, 2017 The third-order particle-hole ring diagrams are evaluated for a NN-contact interaction of the Skyrme type. The pertinent four-loop coefficients in the energy per particle $\bar E(k_f) \sim k_f^{5+2n}$ are reduced to double-integrals over cubic ...
Kaiser, N.
core +1 more source
, 2007 Many research fields are concerned with contacts between objects or between a human and an object. As a first generality, one can say that contact makes the distinction between existence or absence of short distance physical interaction. Furthermore, the notion of contact means a short distance interaction between two physical entities.
Couroussé, Damien, Gil, Jorge Juan
openaire +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source