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The growing impact of infections and the rapid emergence of antibiotic resistance represent a public health concern worldwide. The exponential development in the field of biomaterials and its multiple applications can offer a solution to the problems ...
Miguel A. Ortega+12 more
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A Facile Route to Fabricate CS/GO Composite Film for the Application of Therapeutic Contact Lenses
Traditional contact lenses bring convenience for ophthalmic drug delivery. However, either as contact lenses or as drug carriers, traditional materials have still some drawbacks in the field.
Pin Chen+3 more
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Biological Mineralization of Hydrophilic Intraocular Lenses
Biomaterials calcify upon implantation in contact with biological fluids, which are supersaturated with respect to more than one crystalline phase of calcium phosphate.
Petros G. Koutsoukos+3 more
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Biocompatible polymers are used for many different purposes (catheters, artificial heart components, dentistry products, etc.). An important field for biocompatible polymers is the production of vision implants known as intraocular lenses or custom-shape
Evaldas Kažukauskas+5 more
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Natural Biological Macromolecules for Designing Hydrogels as Health Care and Anti-aging Solutions
Recent advances in the development of strategies for chemical adaptation of biomacromolecules, such as polysaccharides, proteins, and lipids, have allowed for the design of functional hydrogels suitable for the current requirements in the biomedical and ...
Mariana Chelu, Adina Magdalena Musuc
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Chlorhexidine kinetics of hydrophilic contact lenses
Abstract An average chlorhexidine concentration of 4·5 μg mg−1 lens (wet weight) was measured in HEMA-based contact lenses after 16 days of the following treatment. The lenses were maintained 16 h daily in 1·5 ml of a solution containing Chlorhexidine digluconate 0·005%, and then worn by adult albino rabbits 8 h daily.
Donald L. MacKeen+2 more
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Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs
Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility
Xiaohong Hu+6 more
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The aim of this study was to investigate the possibility of chitosan and regenerated silk fibroin (CS/RSF) blended films as novel biomaterials for daily disposable therapeutic contact lenses based ophthalmic drug delivery system.
Rachasit Jeencham+3 more
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Hydrogels are 3D polymeric networks, which exhibit properties such as softness, viscoelasticity and their ability to absorb large amounts of water. These characteristics make them exceptionally suitable in biomedicine as e.g.
Rekowska Natalia+7 more
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Hydrogel refers to a three-dimensional cross-linked polymeric network made of synthetic or natural polymers that can hold water in its porous structure.
Kumaran Subramanian+10 more
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