Results 41 to 50 of about 1,174,398 (306)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Three-phase contact line and line tension of electrolyte solutions in contact with charged substrates [PDF]
Journal of Physics: Condensed Matter, 2016 The three-phase contact line formed by the intersection of a liquid-vapor interface of an electrolyte solution with a charged planar substrate is studied in terms of classical density functional theory applied to a lattice model. The influence of the substrate charge density and of the ionic strength of the solution on the intrinsic structure of the ...
Ibagon, I., Bier, M., Dietrich, S.
openaire +4 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
High Order Finite Element Solution of Elastohydrodynamic Lubrication Problems [PDF]
, 2006 In this thesis, a high-order finite element scheme, based upon the Discontinuous Galerkin (DG) method, is introduced to solve one- and two-dimensional Elastohydrodynamic Lubrication (EHL) problems (line contact and point contact). This thesis provides an
Lu, Hongqiang
core
A note on Merwin's measurements of forward flow in rolling contact [PDF]
, 2004 The first quantitative analysis of the forward flow in frictionless rolling contact, firstly discovered experimentally by Crook [Proc. Inst. Mech. Eng.
Ciavarella, M. +2 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Superconfinement tailors fluid flow at microscales.
, 2015 Understanding fluid dynamics under extreme confinement, where device and intrinsic fluid length scales become comparable, is essential to successfully develop the coming generations of fluidic devices.
Aarts, Dirk G. +16 more
core +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Contact-line instability of dewetting thin films [PDF]
, 2004 We investigate the linear stability of dewetting thin polymer films on hydrophobised substrates driven by Van-der-Waals forces, using a lubrication model.
Münch, Andreas, Wagner, Barbara
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source