Results 51 to 60 of about 6,166,451 (341)
Nanofriction mechanisms derived from the dependence of friction on load and sliding velocity from air to UHV on hydrophilic silicon [PDF]
, 2005 This paper examines friction as a function of the sliding velocity and applied normal load from air to UHV in a scanning force microscope (SFM) experiment in which a sharp silicon tip slides against a flat Si(100) sample.
A. Opitz +21 more
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Ice-structure impact contact load test setup and impact contact load calculation
, 2014 Shipping in arctic and other ice conditions is increasing. Modern propulsion systems often utilize azimuthing thrusters in their various forms. When operating azimuthing thruster equipped ships in ice conditions, the thruster will interact with ice. One such interaction type is an impact type contact of ice block and thruster.
Kinnunen Aki +2 more
openaire +3 more sources
Механика машин, механизмов и материалов, 2012 In article the experimental analysis of laws of influence of the pressure caused by extracontact loading, on change of the moment of a friction and rolling resistance coefficient is carried out.
V.V. Komissarov
doaj
, 2015 We study numerically local models for the mechanical contact between two solids with rough surfaces. When the solids softly touch either through adhesion or by a small normal load $L$, contact only forms at isolated patches and fluids can pass through ...
Dapp, Wolf B., Müser, Martin H.
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Evaluation of pressure-stiffness coupling in brush seals [PDF]
, 2010 Brush seals are comprised of fine diameter fibers densely packed between retaining and backing plates. To achieve seal compliance bristles are arranged to contact rotor with some lay angle.
Aksit, Mahmut Faruk +2 more
core +1 more source