Results 61 to 70 of about 6,166,451 (341)

Frictional elastic contact with periodic loading

open access: yesInternational Journal of Solids and Structures, 2011
Quasi-static frictional contact problems for bodies of fairly general profile that can be represented as half planes can be solved using an extension of the methods of Ciavarella and Jager. Here we consider the tangential traction distributions developed when such systems are subjected to loading that varies periodically in time.
Barber, JR, Davies, M, Hills, D
openaire   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The Wheel–Rail Contact Force for a Heavy-Load Train Can Be Measured Using a Collaborative Calibration Algorithm

open access: yesInformation
The wheel–rail contact force is a crucial indicator for ensuring the secure operation of a heavy-load train. However, obtaining the real-time wheel–rail contact force of a heavy-load train is a challenging task as, due to safety considerations, it is not
Tianning Wen   +3 more
doaj   +1 more source

THREE-DIMENSIONAL FRACTAL MODEL OF DAMPING FOR TANGENTIAL CONTACT IN JOINT INTERFACES

open access: yesJixie qiangdu, 2021
Based on fractal theory,continuous smooth exponential model of elastic-plastic contact,and considering the influence of friction factors and applying an improved W-M function that simulating three-dimensional fractal profile surface,the fractal model of ...
LAN GuoSheng   +5 more
doaj  

Stryker Osteonics: Prosthetic Knee Joint [PDF]

open access: yes, 2008
We examine, within a simple bearing model of a knee joint that only consideres pure sliding, the effect of the presence of a small vertical hole in the load area on the fluid film properties.
Hjorth, P.G.   +5 more
core  

Nanoindentation Of Si Nanostructures: Buckling And Friction At Nanoscales [PDF]

open access: yes, 2009
A nanoindentation system was employed to characterize mechanical properties of silicon nanolines (SiNLs), which were fabricated by an anisotropic wet etching (AWE) process.
Allen, R. A.   +9 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Law of Friction: from Tribology to Tribo-Fatigue. Report 3. Experimental Studies

open access: yesМеханика машин, механизмов и материалов, 2019
To date, many laws of nature have been discovered. The knowledge of each of them led to the accelerated development of the relevant sections of Science and further, as a rule, to progress in any practical area of the community of people.
Leonid A. Sosnovskiy
doaj  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

A semi-analytical approach to the elastic loading behaviour of rough surfaces

open access: yesFriction, 2019
The elastic loading behaviour of rough surfaces is derived based on the physical understanding of the contact phenomena, where the pressure distribution is analytically obtained without any negative values or convergence problems, thus the evolution of ...
Xiaogang Zhang, Yali Zhang, Zhongmin Jin
doaj   +1 more source

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