Results 91 to 100 of about 2,661,721 (287)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
THE CONVERTER FORMS OF A VOLTAGE TO THE SYSTEM POWER SUPPLY CONTACT SYSTEM AC
Nauka ta progres transportu, 2009 The structures of sine voltage to quasi-meander shape voltage converters, which allow increasing up to two times the traffic carrying capacity of the feeder mains, are considered.
N. V. Panasenko +6 more
doaj
Leveraging H1N1 infection transmission modeling with proximity sensor microdata
BMC Medical Informatics and Decision Making, 2012 Background The contact networks between individuals can have a profound impact on the evolution of an infectious outbreak within a network. The impact of the interaction between contact network and disease dynamics on infection spread has been ...
Hashemian Mohammad +2 more
doaj +1 more source
Effect of Coupling on the Epidemic Threshold in Interconnected Complex Networks: A Spectral Analysis
, 2012 In epidemic modeling, the term infection strength indicates the ratio of infection rate and cure rate. If the infection strength is higher than a certain threshold -- which we define as the epidemic threshold - then the epidemic spreads through the ...
Chowdhury, Fahmida N. +2 more
core +1 more source
Interacting Epidemics and Coinfection on Contact Networks
PLoS ONE, 2013 9 pages, 3 ...
M E J Newman, Carrie R Ferrario
openaire +5 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
THE ELECTROSTATIC CHARACTERISTICS OF LINEAR INSULATORS FOR CONTACT NETWORKS OF RAILWAYS
Nauka ta progres transportu, 2009 On the base of numeric investigations on mathematical models of stationary electric field the basic electric performances of insulating suspensions from porcelain and polymeric insulators for contact nets of alternating and direct current are compared.
Ye. D. Kim +2 more
doaj
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source