Results 51 to 60 of about 530,557 (235)
Nauka ta progres transportu, 2012 It is considered the methods of expert systems for automation of the operative control of a condition of the scheme of a contact network of traction electrosupply of the railway. It is designated the directions of researches on formation of structure of
D.V. Voytikov
doaj
Genotyping Oral Commensal Bacteria to Predict Social Contact and Structure. [PDF]
PLoS ONE, 2016 Social network structure is a fundamental determinant of human health, from infectious to chronic diseases. However, quantitative and unbiased approaches to measuring social network structure are lacking.
Stephen Starko Francis +3 more
doaj +1 more source
Analytics for directed contact networks [PDF]
Applied Network Science, 2019 AbstractDirected contact networks (DCNs) are temporal networks that are useful for analyzing and modeling phenomena in transportation, communications, epidemiology and social networking. Specific sequences of contacts can underlie higher-level behaviors such as flows that aggregate contacts based on some notion of semantic and temporal proximity.
George Cybenko, Steve Huntsman
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
How to Estimate Epidemic Risk from Incomplete Contact Diaries Data? [PDF]
PLoS Computational Biology, 2016 Social interactions shape the patterns of spreading processes in a population. Techniques such as diaries or proximity sensors allow to collect data about encounters and to build networks of contacts between individuals.
Rossana Mastrandrea, Alain Barrat
doaj +1 more source
Refined Contact Map Prediction of Peptides Based on GCN and ResNet
Frontiers in Genetics, 2022 Predicting peptide inter-residue contact maps plays an important role in computational biology, which determines the topology of the peptide structure. However, due to the limited number of known homologous structures, there is still much room for inter ...
Jiawei Gu +9 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Contact Heterogeneity and Phylodynamics: How Contact Networks Shape Parasite Evolutionary Trees [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2011 The inference of population dynamics from molecular sequence data is becoming an important new method for the surveillance of infectious diseases. Here, we examine how heterogeneity in contact shapes the genealogies of parasitic agents. Using extensive simulations, we find that contact heterogeneity can have a strong effect on how the structure of ...
Eamon B. O'Dea, Claus O. Wilke
openaire +3 more sources