Results 61 to 70 of about 530,557 (235)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

VSTP: vessel spatio-temporal contact pattern detection based on MapReduce

open access: yesEURASIP Journal on Wireless Communications and Networking, 2017
Due to lack of the coverage of 3G/4G network, satellite communication which costs excessively is the main approach used in ocean to provide network service. Ocean mobile delay tolerant network (OMDTN) can provide low-cost data transmission service in the
Chao Liu   +5 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

ANCA: A Web Server for Amino Acid Networks Construction and Analysis

open access: yesFrontiers in Molecular Biosciences, 2020
Amino acid network (AAN) models empower us to gain insights into protein structures and functions by describing a protein 3D structure as a graph, where nodes represent residues and edges as amino acid interactions.
Wenying Yan   +4 more
doaj   +1 more source

Contact Trees: Network Visualization beyond Nodes and Edges. [PDF]

open access: yesPLoS ONE, 2016
Node-Link diagrams make it possible to take a quick glance at how nodes (or actors) in a network are connected by edges (or ties). A conventional network diagram of a "contact tree" maps out a root and branches that represent the structure of nodes and ...
Arnaud Sallaberry   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

THE CONVERTER FORMS OF A VOLTAGE TO THE SYSTEM POWER SUPPLY CONTACT SYSTEM AC

open access: yesNauka ta progres transportu, 2009
The structures of sine voltage to quasi-meander shape voltage converters, which allow increasing up to two times the traffic carrying capacity of the feeder mains, are considered.
N. V. Panasenko   +6 more
doaj  

Epidemic contact tracing via communication traces.

open access: yesPLoS ONE, 2014
Traditional contact tracing relies on knowledge of the interpersonal network of physical interactions, where contagious outbreaks propagate. However, due to privacy constraints and noisy data assimilation, this network is generally difficult to ...
Katayoun Farrahi   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

THE ELECTROSTATIC CHARACTERISTICS OF LINEAR INSULATORS FOR CONTACT NETWORKS OF RAILWAYS

open access: yesNauka ta progres transportu, 2009
On the base of numeric investigations on mathematical models of stationary electric field the basic electric performances of insulating suspensions from porcelain and polymeric insulators for contact nets of alternating and direct current are compared.
Ye. D. Kim   +2 more
doaj  

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