Results 71 to 80 of about 364,146 (257)

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman, Maria Yasmine, Dunia Hatabah, Noor Alzraikat, Frank Harris, Lou Ann Brown, Satheesh Chonat, Nitya Bakshi, Chris A. Rees, Carlton Dampier, Claudia R. Morris   +10 more
wiley   +1 more source

Threshold-Coloring and Unit-Cube Contact Representation of Graphs [PDF]

, 2013
In this paper we study threshold coloring of graphs, where the vertex colors represented by integers are used to describe any spanning subgraph of the given graph as follows. Pairs of vertices with near colors imply the edge between them is present and pairs of vertices with far colors imply the edge is absent.
Md. Jawaherul Alam, Steven Chaplick, Gasper Fijavz, Michael Kaufmann 0001, Stephen G. Kobourov, Sergey Pupyrev   +5 more
openaire   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

View-Based 3D Model Retrieval by Joint Subgraph Learning and Matching

IEEE Access, 2020
View-based 3D model retrieval is an important and challenging task in computer vision, which can be utilized in many applications such as landmark detection, image set classification, etc.
Haipeng Guan, Qiuxia Zhao, Yan Ren, Weizhi Nie   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Wear Analysis of Catenary Dropper Lines Due to Discontinuous Contact

Applied Sciences
The service reliability of critical catenary components is strongly influenced by damage evolution at dynamic contact interfaces. In this study, a numerical framework is developed to simulate the dynamic contact behavior and wear progression of catenary ...
Cong Chen, Huai Zhao, Duorun Wang, Xingyu Feng, Guilin Liu, Jiliang Mo, Jian Luo, Dabing Luo   +7 more
doaj   +1 more source

On layered area-proportional rectangle contact representations

Theoretical Computer Science
Semantic word clouds visualize the semantic relatedness between the words of a text by placing pairs of related words close to each other. Formally, the problem of drawing semantic word clouds corresponds to drawing a rectangle contact representation of a graph whose vertices correlate to the words to be displayed and whose edges indicate that two ...
Carolina Haase, Philipp Kindermann
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source