Results 71 to 80 of about 2,200,532 (289)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Preliminary Evaluation for the Performance of Circuit Breaker Mediated by SF6 Gas [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2020
The objectives of this paper are to measure the resistance of insulation and contact, simultaneously the CB’s contact when opened/closed operations; and the quality of SF6 gas.
GOERITNO Arief
doaj  

Silicon switching transistor with high power and low saturation voltage [PDF]

open access: yes, 1973
Assembly of two individually encapsulated silicon-chip transistors produces silicon power-transistor that has low electrical resistance and low thermal impedance.
Ferree, H.   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Finite element based surface roughness study for ohmic contact of microswitches [PDF]

open access: yes, 2012
Finite element method (FEM) is used to model ohmic contact in microswitches. A determinist approach is adopted, including atomic force microscope (AFM) scanning real contact surfaces and generating rough surfaces with three-dimensional mesh.
Broue, Adrien   +4 more
core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Electric Life of Vacuum Circuit Breaker Considering High-speed Trains Passing Neutral Sections

open access: yes机车电传动, 2012
For the vacuum circuit breaker (VCB) breaking frequently in high-speed railway, contacts were repeatedly corroded, and tips, coarsenesses and reduction of vacuum degree of diffusing metal vapor were caused by arc during breaking. The experimental program
LI Tian-zhi   +4 more
doaj  

Combined scanning probe electronic and thermal characterization of an indium arsenide nanowire

open access: yesBeilstein Journal of Nanotechnology, 2018
As electronic devices are downsized, physical processes at the interface to electrodes may dominate and limit device performance. A crucial step towards device optimization is being able to separate such contact effects from intrinsic device properties ...
Tino Wagner   +4 more
doaj   +1 more source

Thermal and electrical contact conductance studies [PDF]

open access: yes
Prediction of electrical and thermal contact resistance for pressed, nominally flat contacts is complicated by the large number of variables which influence contact formation.
Nilles, M., Vansciver, S. W.
core   +1 more source

Home - About - Disclaimer - Privacy