Results 71 to 80 of about 2,200,532 (289)
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Preliminary Evaluation for the Performance of Circuit Breaker Mediated by SF6 Gas [PDF]
The objectives of this paper are to measure the resistance of insulation and contact, simultaneously the CB’s contact when opened/closed operations; and the quality of SF6 gas.
GOERITNO Arief
doaj
Silicon switching transistor with high power and low saturation voltage [PDF]
Assembly of two individually encapsulated silicon-chip transistors produces silicon power-transistor that has low electrical resistance and low thermal impedance.
Ferree, H. +2 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Finite element based surface roughness study for ohmic contact of microswitches [PDF]
Finite element method (FEM) is used to model ohmic contact in microswitches. A determinist approach is adopted, including atomic force microscope (AFM) scanning real contact surfaces and generating rough surfaces with three-dimensional mesh.
Broue, Adrien +4 more
core +3 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Electric Life of Vacuum Circuit Breaker Considering High-speed Trains Passing Neutral Sections
For the vacuum circuit breaker (VCB) breaking frequently in high-speed railway, contacts were repeatedly corroded, and tips, coarsenesses and reduction of vacuum degree of diffusing metal vapor were caused by arc during breaking. The experimental program
LI Tian-zhi +4 more
doaj
Combined scanning probe electronic and thermal characterization of an indium arsenide nanowire
As electronic devices are downsized, physical processes at the interface to electrodes may dominate and limit device performance. A crucial step towards device optimization is being able to separate such contact effects from intrinsic device properties ...
Tino Wagner +4 more
doaj +1 more source
Thermal and electrical contact conductance studies [PDF]
Prediction of electrical and thermal contact resistance for pressed, nominally flat contacts is complicated by the large number of variables which influence contact formation.
Nilles, M., Vansciver, S. W.
core +1 more source

