Results 71 to 80 of about 589,209 (313)

New direct contact approach to evaluate soil genotoxicity using the Vicia faba micronucleus test. [PDF]

, 2009
A method to assess micronucleus (MN) induction in Vicia faba roots by direct contact exposure to a solid matrix was developed. The procedure comprised a 5-d germination period, as in the well-known method using aqueous extracts.
Cecchi, Marie, Cotelle, Sylvie, Guiresse, Agnès Maritchù, Marcato, Claire-Emmanuelle, Pinelli, Eric   +4 more
core   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

An environmentally benign antimicrobial nanoparticle based on a silver-infused lignin core [PDF]

, 2015
Silver nanoparticles have antibacterial properties, but their use has been a cause for concern because they persist in the environment. Here, we show that lignin nanoparticles infused with silver ions and coated with a cationic polyelectrolyte layer form
A Duval, A Kumar, A Panáček, A Panáček, A Verma, AE Nel, Alexander P. Richter, AM El Badawy, Amy Wang, Bhuvnesh Bharti, C Frangville, C Ge, C Levard, C Wandrey, E Jeong, Elaine A. Cohen Hubal, G Marchant, GA Sotiriou, H Harmita, H Lara, HA Wege, I Sondi, J Dobias, J Fabrega, Joseph S. Brown, JR Morones, K Lundquist, K Poole, Keith Houck, L Petridis, M Ahamed, M Lundqvist, M Norgren, M Rai, MP Monopoli, O Choi, Orlin D. Velev, P Anastas, P Gélinas, P Raveendran, QL Feng, R Justo-Hanani, R Kavlock, S Kim, S Langsrud, S Tan, Simeon D. Stoyanov, SL Chinnapongse, ST Stern, Sumit Gangwal, T Silva, T Walser, TDH Bugg, Vesselin N. Paunov, VK Sharma, VK Sharma, X Guo, Y Matsumura, Z Xiu   +58 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Acute Contact Toxicity of Six Pesticides in Honeybees (Apis Mellifera Meda) in Iran

Journal of Apicultural Science, 2017
Pollination has an important role in both agricultural production and wild plant reproduction. For the pollination of crops, agriculture relies largely on managed colonies of the honeybee Apis mellifera.
Rasuli Farhang, Rafie Javad Nazemi, Sadeghi Amin   +2 more
doaj   +1 more source

The Effect of Natural Dissolved Organic Carbon on the Acute Toxicity of Copper to Larval Freshwater Mussels (\u3cem\u3eGlochidia\u3c/em\u3e) [PDF]

, 2010
The present study examined the effect of dissolved organic carbon (DOC), both added and inherent, on Cu toxicity in glochidia, the larvae of freshwater mussels.
Ackerman, Josef D., Gillis, Patricia L., Mackie, Gerald L., McGeer, James C., Wilkie, Michael P.   +4 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Performance of Mineral and Plant-Derived Dusts Against the Cabbage Stink Bug (Eurydema ventralis Kolenati) on Brassica Leaves: Mortality and Feeding Injury

Horticulturae
Eurydema ventralis has recently intensified in Brassica production in Central and Southeastern Europe, increasing the need for alternatives to conventional insecticides.
Luka Batistič, Stanislav Trdan
doaj   +1 more source

Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. [PDF]

, 2019
BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use.
(Environmental influences on Child Health Outcomes), Beamer, Paloma I, Bennett, Deborah H, Boyles, Rebecca R, Buckley, Jessie P, Kannan, Kurunthachalam, Pellizzari, Edo D, Wang, Aolin, Woodruff, Tracey J, Zhu, Yeyi   +9 more
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source