Results 231 to 240 of about 877,646 (303)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Ventilation-perfusion effects of negative-pressure ventilation: insights from an experimental rat model. [PDF]

open access: yesIntensive Care Med Exp
Fodor GH   +5 more
europepmc   +1 more source

Detection of novel <i>Wolbachia</i> strains in <i>Aedes aegypti</i> populations from a recent arbovirus outbreak region in Pune District, Maharashtra, India (2024). [PDF]

open access: yesFront Microbiol
Hari I   +13 more
europepmc   +1 more source

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