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Forecasting resource availability for supporting real-time container migration [PDF]
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2024-08-01The student, Vishakh Suresh Babu, accepted the attached license on 2022-07-20 at 15:45.The student, Vishakh Suresh Babu, submitted this Thesis ...
Suresh Babu, Vishakh
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London [PDF]
Zapata GP. The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London. COMCAD Arbeitspapiere - Working Papers, 106.
Zapata, Gisela P.
core
Optimization problems running MPI-based HPC applications
MPI is a well-proven technology that is widely used in a high-performance computing environment. However, configuring an MPI cluster can be a difficult task.
D. A. Grushin, N. N. Kuzjurin
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Public opinion on migration [PDF]
Mapping and understanding what shapes public attitudes are particularly critical at a time when immigration is often perceived as one of the most important political issues facing countries around the world, with significant implications for election ...
DENNISON, James
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source

