Results 151 to 160 of about 150,874 (288)

Execution-bound advisory automation for agentic AI: a reproducible AIBOM-driven CSAF-VEX framework. [PDF]

Front Artif Intell
Radanliev P, Santos O, Maple C, Atefi K.
europepmc   +1 more source

Container Orchestration for the Edge Cloud

Orchestration de conteneurs pour l'edge cloud Avec l'essor des infrastructures de type edge où les ressources informatiques sont en périphérie de réseau, la tendance est une fois de plus orientée vers la décentralisation. En plus des appareils à ressources contraintes qui peuvent effectuer des tâches limitées, le « edge cloud » se ...
openaire   +2 more sources

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Systems-Level Support for Hybrid Quantum-Classical Learning: A Systematic Review with a Medical Imaging Translation Lens. [PDF]

J Imaging
Rahman M, Paul PC, Begum A, Sultana K, Akter N, Majumder A, Zhu M, Sheng Z, Xin W, Jin X, Zhuang J.   +10 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Towards a sustainable astronomical data infrastructure: Optimising linking data from the Rucio datalake to the users areas within the SKA Regional Centres Network. [PDF]

Open Res Eur
Parra-Royón M, Garrido-Sánchez J, Sánchez-Expósito S, Darriba-Pol L, Sánchez-Castañeda J, Mendoza MÁ, Coles J, McConkey S, Joshi R, Barnsley R, Salgado J, Verdes-Montenegro L.   +11 more
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Fedflow: cloud orchestration for federated learning with the FeatureCloud platform. [PDF]

Bioinform Adv
Weilguny L, Probul N, Ren Y, Pons N, Baumbach J, Almeida M.   +5 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

A Modular Active-Reactive AAS Architecture for Mass-Customized Production: Validation on an Industrial-Grade Robotic Screwdriving Demonstrator. [PDF]

Sensors (Basel)
Silva ARAD, Cardoso FS, Postigo MAO, Torné IG, Takano YL, Almeida LPA, Souza MWP, Lucas AHT.   +7 more
europepmc   +1 more source