Results 221 to 230 of about 150,874 (288)

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

RareCure: An Open-Source Artificial Intelligence Pipeline for Context-Adaptive Treatment Discovery in Rare Solid Tumors. [PDF]

Cureus
Arogyasami D.
europepmc   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

A Governance-Aware Private Cloud Architecture for Scalable Multi-Provider Vehicle-Based Multimodal Sensing. [PDF]

Sensors (Basel)
Kunić Z, Dakić V, Morić Z.
europepmc   +1 more source

A Centralized AI Lakehouse Framework for Brain Tumor MRI Classification and Segmentation, University KPI Forecasting, and Water Potability Prediction. [PDF]

Sensors (Basel)
Shrestha R, Rana MM, Sun B, Sun F, Lou H, Hutson A.   +5 more
europepmc   +1 more source

Enhancing Gen3 for clinical trial time series analytics and data discovery: a data commons framework for NIH clinical trials. [PDF]

Front Digit Health
Adams MCB, Griffin C, Adams H, Bryant S, Hurley RW, Topaloglu U.   +5 more
europepmc   +1 more source

Ontology- and LLM-based data harmonization for federated learning in healthcare. [PDF]

Front Digit Health
Kokash N, Wang L, Gillespie TH, Belloum ASZ, Grosso P, Quinney S, Li L, de Bono B.   +7 more
europepmc   +1 more source

MHub.ai: A Standardized Platform for Reproducible AI Research in Medical Imaging

Aerts H, Nürnberg L, Bontempi D, Pai S, Lisle C, Pieper S, Kikinis R, de Leemput Sv, Soni R, Murugesan G, Ciausu C, Groeneveld M, Dorfner F, Jiang J, Rangnekar A, Veeraraghavan H, Bosma J, Bressem K, Mak R, Fedorov A.   +19 more
europepmc   +1 more source

AI-based secure event-driven serverless architecture for scalable digital civic participation platform. [PDF]

Front Artif Intell
Kassymova A, Razaque A, Uskenbayeva R, Kalpeyeva Z, Anartayeva A.   +4 more
europepmc   +1 more source

PipeBench: a benchmarking framework for end-to-end machine learning pipelines. [PDF]

Sci Rep
Agal S, Katariya R.
europepmc   +1 more source