Results 141 to 150 of about 767,915 (254)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Empirical Analysis on Productivity of Container Terminal in Tanzanian: A Case of Dar es Salaam Port General Cargo Container Terminal [PDF]
, 2018 This thesis presents an empirical analysis on productivity of Dar es Salaam Port General Cargo Container Terminal (DSM Port GCCT). The study examined productivity of DSM Port GCCT; determined DSM Port GCCT productivity model; and analysed future trend of
Mwisila, Lucas Pastory
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
ANALISIS TERHAMBATNYA PENATAAN CONTAINER EKSPOR PADA CONTAINER YARD DI TERMINAL PETI KEMAS SEMARANG
, 2018 Sebagai pelabuhan lalu lintas angkutan barang, keberadaan Terminal Peti Kemas Semarang sangat diperlukan oleh dunia industri untuk mendukung kelancaran ekspor container.
Firhand, Aulia Ramadhan
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Το μοντέλο Δέλτα στο container terminal του ΟΛΠ Α.Ε.
, 2012 Η εφαρμογή του μοντέλου δέλτα στο container terminal του ΟΛΠ Α ...
Καριπίδου, Ειρήνη
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Transportation Optimization Modeling for Washington State Hay Shipments: Mode and Cost Implications Due to Loss of Container Services at the Port of Portland [PDF]
A recent issue impacting hay shipments in Washington State involves the reduction of container services at the Port of Portland, Oregon. Prior to this change, containers filled with hay were shipped almost exclusively via barge on the Columbia River to ...
Meenach, Stephanie +2 more
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