Results 171 to 180 of about 1,548,849 (348)

A systemic analysis of container terminal layouts

open access: yesJournal of Shipping and Trade
The paper provides a systemic analysis of the layout characteristics of a geodatabase comprised of a large sample of 331 global container terminals.
Jean-Paul Rodrigue
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Optimisation of container process at multimodal container terminals [PDF]

open access: yes, 2008
Multimodal container terminals are an important part of the logistics systems in international trade. Any improvement in the terminal efficiency is likely to reduce the costs of transporting goods, and to strengthen the trading position of the nation ...
Wong, Andy King-sing
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

TECHNICAL EFFICIENCY OF CONTAINER TERMINAL OPERATIONS: A DEA APPROACH [PDF]

open access: yes, 2013
 Nowadays, transporting cargoes via container are key indicator for every shipment. The movement of container involves multi modes to reach destination.
Mokhtar, Kasypi
core   +1 more source

Malmquist Productivity Index for Container Terminal [PDF]

open access: yes, 2013
The current decade sees significant growth in worldwide seaborne container transportation and with it an essential need for optimization of its productivity.
Zaly Shah, Muhammad, Mokhtar, Kasypi
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Container Terminal Planning And Capacity Analysis [PDF]

open access: yes, 2015
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2006Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2006Bu yüksek lisans tez çalışmasında konteyner terminali planlamasının temelleri ...
Büyüközer, A. Avni
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Transshipment container terminals

open access: yes, 2020
The ever increasing number of containers to be transported necessitates expanding thecapacity of container terminals. This can be achieved either by enlarging the containerterminals physically or by managing the container terminals better. Since the first alternative is costly, and sometimes not possible due to limited land, container terminal managers
openaire   +1 more source

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