Results 111 to 120 of about 45,740 (299)

Multicriteria Decision Model for Port Evaluation and Ranking: An Analysis of Container Terminals in Latin America and the Caribbean Using PCA-TOPSIS Methodologies

open access: yesApplied Sciences
In recent years, despite a decline in international trade and disruptions in the supply chain caused by COVID-19, the main container terminals in Latin America and the Caribbean (LAC) have increased their container volumes.
Adriana Pabón-Noguera   +5 more
doaj   +1 more source

Dynamic Scheduling of Handling Equipment at Automated Container Terminals [PDF]

open access: yes
In this paper we consider the problem of integrated scheduling of various types of handling equipment at an automated container terminal in a dynamic environment.
Meersmans, P.J.M., Wagelmans, A.P.M.
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Container Terminal Concession Guidelines

open access: yes, 2017
The decision, by a national government or a port authority, to contract out the development and operation of a container terminal facility to a qualified private operator sets in motion a process involving relationships with quite a different set of players compared to traditional port operations and management.
openaire   +2 more sources

Container Train Operators in India: Problems and Prospects [PDF]

open access: yes
In India, railways are under the control of the government which is the sole provider of the infrastructure, operations and regulatory functions. Private participation, though very limited, was largely in the domain of infrastructure creation. In January
Gangwar, Rachna, Raghuram, G.
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

L-band, 1.2 m parabolic antenna-noise temperature measurement [PDF]

open access: yes, 1975
Extensive antenna-noise temperature measurements at 1.6 GHz (L-band) were made using a 1.2 m (4 ft. diameter) parabolic dish antenna mounted on the flying bridge of a modern 15,690-ton, commercial-container ship.
Hill, J. S., Taylor, R. E.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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