Results 111 to 120 of about 7,283 (299)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Reforms and infrastructure efficiency in Spain's container ports [PDF]

This paper quantifies the evolution of technical efficiency in port infrastructure service provision in the major Spanish port authorities involved in container traffic. The paper also analyzes the extent to which port reforms that took place in the 1990'
Trujillo, Lourdes, Gonzalez, Maria Manuela   +1 more
core  

Multicriteria Decision Model for Port Evaluation and Ranking: An Analysis of Container Terminals in Latin America and the Caribbean Using PCA-TOPSIS Methodologies

Applied Sciences
In recent years, despite a decline in international trade and disruptions in the supply chain caused by COVID-19, the main container terminals in Latin America and the Caribbean (LAC) have increased their container volumes.
Adriana Pabón-Noguera, María Gema Carrasco-García, Juan Jesús Ruíz-Aguilar, María Inmaculada Rodríguez-García, María Cerbán-Jimenez, Ignacio José Turias Domínguez   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

ICT EVOLUTION IN CONTAINER TERMINALS [PDF]

, 2010
Informacijske i komunikacijske tehnologije (ICT) osnova su za implementaciju suvremenih logističkih procesa na kontejnerskim terminalima. ICT-e posjeduju veliki potencijal za korištenje u različitim aktivnostima kontejnerskih terminala.
Hlača, Bojan, Tijan, Edvard, Adrijana Agatić, Agatić, Adrijana, Bojan Hlača, Edvard Tijan   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

An evaluation of Nigerian ports post-concession performance [PDF]

Purpose: The quest for efficiency is claimed to be the major objective of port privatisation and this has led many ports in Africa to undertake port reforms.
Nwanosike, F., Warnock-Smith, David, Tipi, Nicoleta S.   +2 more
core  

Improving the productivity of marine container terminals [PDF]

, 2000
The research presented in this thesis is concerned with several facets of the management of container terminals. One facet, of the research was to test the hypothesis that it is difficult to compare the productivities of container terminals.
Behera, Jyotirmaya
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source