Results 71 to 80 of about 45,740 (299)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
A viral system to optimise the daily drayage problem [PDF]
, 2015 The intermodal transport chain can become more efficient by means of a good organisation of the drayage movements. Drayage in intermodal container terminals involves the pick up or delivery of containers at customer locations, and the main objective is ...
Aparicio Ruiz, Pablo +3 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Maritime Commerce in Greater Philadelphia: Assessing Industry Trends and Growth Opportunities for Delaware River Ports [PDF]
, 2008 Maritime Commerce in Greater Philadelphia: Assessing Industry Trends and Growth Opportunities for Delaware River Ports is an evaluation of existing port conditions along the Delaware River and market-driven opportunities for expansion.
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
LogisticsBackground: Improving container terminal efficiency requires a comprehensive understanding of the interactions between vessel, truck, and container operations, yet existing studies often analyzed these components separately.
Daigo Shiraishi +3 more
doaj +1 more source
Modeling an offshore container terminal: the Venice case study [PDF]
, 2016 In order to reduce marine transportation times and related costs, as well as the environmental impacts, an alternative multimodal route to the current Suez-Gibraltar-North Sea corridor for the containers shipped from Far and Middle East was identified as
Baldassarra, Alessandro +3 more
core
Containerisation in the Baltic Sea region: development, characteristics and contemporary organisation [PDF]
, 2019 The main focus of the paper is on the container system development in the Baltic Sea Region studying cotemporary changes and organisation, as well as explaining the main driving forces of this situation.
Serry, Arnaud
core +4 more sources