Results 111 to 120 of about 3,134 (252)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Investigation of container strength when fixed in an open wagon equipped with pneumatic bags

open access: yesActa Technica Jaurinensis
Ensuring the efficiency of railway transport in international traffic needs the development of combined transport systems. Container transportation is the most relevant among them. Containers are usually transported by rail on platform wagons. Along with
Alyona Lovska   +3 more
doaj   +1 more source

The Impact of Port Technical Efficiency on Mediterranean Container Port Competitiveness

open access: yes
Port efficiency is a significant element that stimulates port competitiveness and enhances regional development. With increasing international maritime traffic and changing technology in the maritime transport sector, containerisation and enhanced ...
Elsayeh, Mohi-Eldin
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Developing a container freight information system to understand container truck traffic in inland port cities

open access: yes, 2011
Container freight is an important component of the transportation system yet there is little understanding about this issue. This research develops an information system to assist transportation engineers and planners understand container freight ...
Rempel, Garreth
core  

Influence of Port Policy on the Development of Croatian Container Ports

open access: yes, 2002
It is important to consider the port development throughoutthe world from the aspect of economical, transport and portpolicy and their mutual impact on commerce and efficiency ofports.
Čedomir Dundović, Neven Grubišić
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

A Simulation based model for the berth allocation and quay crane assignment problem

open access: yes
With the global development of container transport, container terminals have become important nodes in transport networks which serve as hubs for the transshipment of containerized goods from ship to ship or from ship to other transport modes.
Abdel Hafez, M.A.   +3 more
core  

Optirnisation Approach to Container Chain Technology

open access: yes, 2012
This paper deals wiLh the selected optimisation approach tocontainer chain technology, focusing on the consignment ofcwgo from the shipper. The basic characteristics of the containerchain technology are analysed first, followed by establishingthe ...
Livij Jakomin   +3 more
core   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

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