Results 201 to 210 of about 3,134 (252)

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

Advanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru, Priyanka Bhattacharyya, Mingxu You   +2 more
wiley   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Faster and Durable: A Cell‐to‐System Validation of a Low‐Degradation Fast‐Charge Protocol for Li‐Ion Batteries

Advanced Science, EarlyView.
A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni, Francesco Giuseppe Quilici, Davide Cademartori, Claudio Scarpelli, Uways Nurulain Mithoowani, Federica Barontini, Alessandro Ruvio, Monica Puccini, Giovanni Lutzemberger, Maria Paola Carpanese, Antonio Bertei   +10 more
wiley   +1 more source

Demand responsive scheduling of rail container traffic

, 2004
Indra-Payoong, N, Kwan, RSK, Proll, L
openaire   +1 more source

Concessioning and container traffic operations in Nigerian ports

African Journal for the Psychological Study of Social Issues, 2021
This study examined the concept of concessioning and container shipping operations in Nigerian Ports and its effect on ports revenue. It analyzed the improvements in container traffic since concession, trend of container traffic after concession, and its influence on ports revenue. The major objectives however are to ascertain if there is a significant
Ndikom, Obed B. C., Buhari, Sodiq Olusegun, Okezie, Godswil Munachim   +2 more
openaire   +2 more sources

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Traffic Strategy for Mixed Traffic in Container Terminals

2022
Si Han Ng, Reuben Ong, Chenhao Zhou
exaly   +2 more sources

Traffic Flow Simulation of Container Terminal Yard

2010 International Conference on Management and Service Science, 2010
A case study of using simulation to support the road planning of a large container terminal yard in China is presented, which demonstrates the method and procedures of combining discrete event simulation technology with road traffic capacity theory to assist road planning of container terminal yard.
exaly   +2 more sources

Traffic-aware Dynamic Container Deployment on the Network Edge

2021 International Conference on Information Networking (ICOIN), 2021
Multi-access Edge Computing (MEC) offers opportunities for improving the network performance. It can be utilized for improving web application. Every request that is destined for the cloud service providers can be processed at the edge. However, some web applications may have high fluctuation in terms of resource usage, for example e-commerce.
Muhamad Rizka Maulana, Hsiao-Yin Peng, Ying-Cen Lai, Li-Der Chou   +3 more
openaire   +1 more source

Sold to China: Container traffic in the Port of Piraeus

Review of International Economics, 2023
AbstractThis article analyzes the effects of the acquisition of the Port of Piraeus by the Chinese shipping operator COSCO in July 2016 on the organization of container traffic in Europe. Using real‐time container ship positions provided by vessel tracking systems between 2015 and 2019, we study the impact of the privatization of the Greek port on its ...
Koenig, Pamina, Poncet, Sandra, Sanch-Maritan, Mathieu, Duvallet, Claude, Pigné, Yoann   +4 more
openaire   +3 more sources