Results 81 to 90 of about 20,796 (275)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Reliability analysis on railway transport chain

International Journal of Transportation Science and Technology, 2019
This paper divides the time of railway container transport chain into the drayage time by road, the storage time at departure station, the railway transit time and the storage time at arrival station according to operation procedure.
Rong Zhang, Lu Li, Wenliang Jian
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Special Report: The Changing Tide of U.S.-International Container Trade: Differences Among the U.S. Atlantic, Gulf, and Pacific Coasts

This BTS special report examines historical U.S. maritime trends, changes in U.S. trading partners, and current U.S. marine trade patterns. More specifically, it compares container vessel calls, container vessel capacity, and the average deadweight ...
Chambers, Matthew, United States. Department of Transportation. Bureau of Transportation Statistics   +1 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Prerequisites for the modelling of empty container supply chains

Engineering Management in Production and Services, 2017
Containerisation of freight transport significantly facilitates the flow of traded goods between remote destinations. The most important container transport routes link Asia with North America and Europe.
Kuźmicz Katarzyna Anna, Pesch Erwin
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Congestion Reduction Through Efficient Empty Container Movement [Brief] [PDF]

METRANS Project 15-28There is a significant amount of container truck congestion in and around the ports area, and it will most likely worsen as container demand continues to increase.
Carvajal, Santiago, Dessouky, Maged, METRANS Transportation Center (Calif.), University of Southern California. Department of Industrial and Systems Engineering   +3 more
core  

A Two-Stage Automatic Container Code Recognition Method Considering Environmental Interference

Applied Sciences
Automatic Container Code Recognition (ACCR) is critical for enhancing the efficiency of container terminals. However, existing ACCR methods frequently fail to achieve satisfactory performance in complex environments at port gates.
Meng Yu, Shanglei Zhu, Bao Lu, Qiang Chen, Tengfei Wang   +4 more
doaj   +1 more source