Advanced optical measurement techniques for simultaneous fibre orientation and flow analysis complemented by machine learning. [PDF]
Sci RepVaupel T +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Memetic/Metaphorical Digital Twins: Extending Knowledge Co-Creation Across Economics, Architecture, and Beyond. [PDF]
Biomimetics (Basel)Schmitt U.
europepmc +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Development of a Scale to Assess the Safe Disposal of Insulin Pen Needles in Patients With Diabetes: A Delphi Study. [PDF]
Nurs OpenZhang W +5 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Optimizing ATP Isothermal Tests: A Theoretical and Experimental Approach. [PDF]
Entropy (Basel)Martínez-Val Piera JP, Ramos Millán A.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Commentary: Psychology's Questionable Research Fundamentals (QRFs): key problems in quantitative psychology and psychological measurement beyond Questionable Research Practices (QRPs). [PDF]
Front PsycholStaller MS, Koerner S.
europepmc +1 more source