We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
In Situ Analysis of Historical Preservation Fluids in Sealed Containers with Spatially Offset Raman Spectroscopy. [PDF]
Blanco A +6 more
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The role of auditory and haptic cues in object enumeration within containers. [PDF]
Frissen I, Sagou O, Overvliet KE.
europepmc +1 more source
Doctors' knowledge, attitudes, and practices in managing dengue fever amid war: A study in three governmental hospitals in Port Sudan, Red Sea State, Sudan (2024). [PDF]
Ebrahim T +3 more
europepmc +1 more source
Oviposition Behavior of <i>Aedes aegypti</i> and <i>Aedes albopictus</i> (Diptera: Culicidae) from Panama Under Experimental L4-Larval Co-Occurrence Scenarios. [PDF]
Tuñón R +6 more
europepmc +1 more source
High Concordance of Self-Reported and Objective Measures of Antihypertensive Use in Individuals Living with HIV in a Resource-Limited Setting. [PDF]
Jere J +8 more
europepmc +1 more source
Evaluation of the Influence of Bottle Type on the Acquisition of SORS Spectra of Extra Virgin and Virgin Olive Oils. [PDF]
Jiménez-Hernández G +5 more
europepmc +1 more source
Fecal contamination of drinking water from source to point of use and associated factors among households in Debre-Tabor town, Northwest Ethiopia. [PDF]
Gebeyehu FG +6 more
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