Results 231 to 240 of about 641,939 (299)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

In Situ Analysis of Historical Preservation Fluids in Sealed Containers with Spatially Offset Raman Spectroscopy. [PDF]

open access: yesACS Omega
Blanco A   +6 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

High Concordance of Self-Reported and Objective Measures of Antihypertensive Use in Individuals Living with HIV in a Resource-Limited Setting. [PDF]

open access: yesGlob Heart
Jere J   +8 more
europepmc   +1 more source

Evaluation of the Influence of Bottle Type on the Acquisition of SORS Spectra of Extra Virgin and Virgin Olive Oils. [PDF]

open access: yesFoods
Jiménez-Hernández G   +5 more
europepmc   +1 more source

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