Results 121 to 130 of about 1,543 (204)

COVID-19 Pneumonia Diagnosis Using Medical Images: Deep Learning-Based Transfer Learning Approach. [PDF]

JMIRx Med
Dharmik A.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cyber-biological convergence: a systematic review and future outlook. [PDF]

Front Bioeng Biotechnol
Elgabry M, Johnson S.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

"COVID-19 affected me greatly (sigh), imagine I'm being called a mother and yet I'm also a child": the effect of COVID-19 on fertility management practices among women in Nairobi and Kisumu cities, Kenya. [PDF]

Front Glob Womens Health
Kwena ZA, Wekesa P, Gitome S, Okumu S, Ndunyu L, Bukusi E, Himes E, Holt K, Liu J, Vallin J, Suchman L.   +10 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Finding maximum common contractions between phylogenetic networks. [PDF]

Algorithms Mol Biol
Marchand B, Tahiri N, Fard SG, Tremblay-Savard O, Lafond M.   +4 more
europepmc   +1 more source

ON RELIABILITY OF NON-BRANCHING PROGRAMS IN A BASIS CONTAINING THE GENERALIZED CONJUNCTION AT ARBITRARY FAULTS OF COMPUTATIONAL OPERATORS

University proceedings. Volga region. Physical and mathematical sciences, 2017
openaire   +1 more source

2P471 A liposome containing an autonomous DNA computing system inside(50. Non-equilibrium and complex system,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006)

Seibutsu Butsuri, 2006
Koh-ichiroh Shohda, Daisuke Kiga, Masahiro Takinoue, Yoshiyuki Kageyama, Tadashi Sugawara, Akira Suyama   +5 more
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source