Results 91 to 100 of about 506,403 (348)

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma   +2 more
wiley   +1 more source

Enhanced Rheological and Filtration Performance of Drilling Fluids Using Fe3O4/Saponin/Cu(II) Nanocomposites: Synthesis, Characterization, and Application

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Drilling fluids used in high‐performance well operations often struggle to maintain rheological stability, colloidal dispersion, and filtration control under harsh downhole conditions. This study engineered a multifunctional Fe3O4@Saponin/Cu(II) nanocomposite to address these challenges.
Kassem Al Attabi   +9 more
wiley   +1 more source

Contemporary short- and mid-term outcomes of transcatheter aortic valve replacement for nonagenarians in Japan [PDF]

open access: gold, 2020
Hiroshi Kurazumi   +9 more
openalex   +1 more source

The Layout and Size of an Early Pre‐Pottery Neolithic B Small Settlement Revealed by Geophysical Prospection at Harbetsuvan Tepesi in Southeastern Anatolia

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT In Upper Mesopotamia, the transition from the Pre‐Pottery Neolithic A (PPNA) to Pre‐Pottery Neolithic B (PPNB) period, ca. 10 800–10 600 cal. BP, is marked by a series of changes in chipped stone industries, architectural forms, symbolic objects, regional distribution of settlements and long‐distance exchange networks among others.
Toshihiro Tada   +7 more
wiley   +1 more source

Politics vs Market [PDF]

open access: yes, 2006
As China's demand for energy grows, so does its dependence on imported oil. Currently, over 40 percent of China's total oil consumption derives from foreign sources making a supply disruption of the oil import routes an unthinkable blow to its national ...
Mao Yushi
core  

Impact of Evolving Treatment Patterns on Interstitial Lung Disease Progression in Systemic Sclerosis Using the European Scleroderma Trials and Research Database

open access: yesArthritis &Rheumatology, EarlyView.
Objective The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasingly available immunosuppressive therapies (ISTs) and antifibrotic treatments. However, their real‐world use remains unclear.
Corrado Campochiaro   +17 more
wiley   +1 more source

Farmers and Capitalism [PDF]

open access: yes
Most analyses of modern capitalism focus on bargains struck between workers, managers, and owners (and the different types of firms they inhabit). But considering the substantial influence of institutional inertia on modern outcomes, it is necessary to ...
Carney, Richard
core   +1 more source

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