Results 41 to 50 of about 7,962,786 (321)

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

What types of pets associate with well-being of their owners in Japan?

Human-Animal Interactions
Background: Research findings on the relationship between pet ownership and well-being are inconsistent. One reason for this inconsistency is inadequate differentiation between pet types.
Itaru Ishiguro
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Occupational stress and burnout among Japanese early childhood education and care teachers: the mediating role of psychological safety

Health Psychology and Behavioral Medicine
Background Early childhood education and care (ECEC) teachers in Japan experience high levels of occupational stress, placing them at significant risk of burnout.
Yuko Matsuda, Shoko Hamada
doaj   +1 more source

Human‐geographic effects on variations in the population genetics of Sinotaia quadrata (Gastropoda: Viviparidae) that historically migrated from continental East Asia to Japan

Ecology and Evolution, 2020
Background Anthropogenic factors potentially affect observed biogeographical patterns in population genetics, but the effects of ancient human activities on the original patterns created by natural processes are unknown.
Bin Ye, Takumi Saito, Takahiro Hirano, Zhengzhong Dong, Van Tu Do, Satoshi Chiba   +5 more
doaj   +1 more source

Oral glucocorticoids added to ILD‐modifying therapy in systemic sclerosis‐associated interstitial lung disease: a target trial emulation study from the EUSTAR database.

Arthritis Care &Research, Accepted Article.
Objectives We aimed to estimate whether adding oral glucocorticoids to ILD‐modifying therapy improves 12‐month lung outcomes in systemic sclerosis‐associated interstitial lung disease (SSc‐ILD). Methods We emulated a target trial using the EUSTAR database.
Zubeyir Salis, Simona Truglia, Oliver Distler, Gábor Kumánovics, Gianluca Moroncini, David Launay, Silvia Bellando‐Randone, Gonçalo Boleto, Nicoletta Del Papa, Ana Maria Gheorghiu, Duygu Temiz Karadag, Zguro Batalov, Gabriella Szucs, Michele Iudici, The EUSTAR collaborators   +14 more
wiley   +1 more source

Diagnostic specificity of the child psychosis-risk screening system with a focus on the differentiation of schizophrenia spectrum disorders and neurodevelopmental disorders

Frontiers in Child and Adolescent Psychiatry, 2023
BackgroundResearch on early psychosis has begun to identify psychiatric characteristics of the prodromal period of schizophrenia; however, subclinical characteristics of children in non-psychiatric fields have not been fully investigated. In our previous
Yukiko Hamasaki, Yukiko Hamasaki, Yuko Sakaue, Masahiro Matsuo, Riku Sanada, Takao Nakayama, Shugo Michikoshi, Satoko Ueba, Naoki Kurimoto, Naoki Kurimoto, Takatoshi Hikida, Toshiya Murai   +11 more
doaj   +1 more source

High‐Modulus Skeleton‐Reinforced PDMS Microstamps for Precision Transfer Printing of Microscale Devices

Advanced Functional Materials, EarlyView.
Elastomeric micropillars bend under contact loading, sliding microscale devices out of alignment during transfer printing. A hybrid PDMS stamp embeds a high‐modulus skeleton within each pillar while retaining a compliant contact surface. The reinforcement confines pillar deformation, suppressing interfacial sliding and preserving array registration on ...
Seol Ahn, Yulin Zhou, Jeongmin Seo, Seong Woo Hong, Sungyeon Kim, Seohyeon Kim, Haechang Ryu, Raudel Avila, Yei Hwan Jung   +8 more
wiley   +1 more source

Acceptance of aging among Japanese adults aged 20–89

Cogent Psychology
Objectives Acceptance of awareness of age-related change (AARC) is vital for mental health, yet the mechanisms underlying this process remain unclear.
Miho Nakajima, Hikari Kinjo
doaj   +1 more source

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

Advanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching, Hinako Ichikawa, Aya Motoyoshi, Shin Tanaka, Liam Morrow, Satoshi Shirae, Noriko Sakai, Shohei Kitahata, Michiko Mandai, Kazuaki Kadonosono   +9 more
wiley   +1 more source