Results 101 to 110 of about 398,603 (343)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Privacy-Aware Multipath Video Caching for Content-Centric Networks [PDF]

open access: green, 2016
Qinghua Wu   +5 more
openalex   +1 more source

A Cache Management Scheme for Efficient Content Eviction and Replication in Cache Networks

open access: yesIEEE Access, 2017
To cope with the ongoing changing demands of the internet, `in-network caching' has been presented as an application solution for two decades. With the advent of information-centric network (ICN) architecture, `in-network caching' becomes a network level
Muhammad Bilal, Shin-Gak Kang
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Evaluating CRoS-NDN: a comparative performance analysis of a controller-based routing scheme for named-data networking

open access: yesJournal of Internet Services and Applications, 2019
The huge amount of content names available in Named-Data Networking (NDN) challenges both the required routing table size and the techniques for locating and forwarding information. Content copies and content mobility exacerbate the scalability challenge
João Vitor Torres   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A More Scalable Approach to Content Centric Networking [PDF]

open access: yes2015 24th International Conference on Computer Communication and Networks (ICCCN), 2015
On-demand Content Exchange with Adaptive Naming (OCEAN) is introduced as an alternative to content centric networking approaches (NDN and CCN) that require the maintenance of forwarding state of each Interest traversing a router in a Pending Interest Table (PIT). Content routers in OCEAN maintain data answer routing tables (DART) to support the correct
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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