Results 61 to 70 of about 4,501 (286)
Content-Centric Mobile Edge Caching
IEEE Access, 2020 With the explosion of data volume, it becomes challenging to deliver high quality service to mobile users. Therefore, edge caching has received significant attentions since it can bring contents near mobile users, to boost spectral efficiency, and reduce
Tiankui Zhang +3 more
doaj +1 more source
Network Function Virtualization in Content-Centric Networks
Anais do X Workshop de Pesquisa Experimental da Internet do Futuro (WPEIF 2019), 2019 Network Functions Virtualization (NFV) offers an alternative way to design, deploy, and manage networking functions and services by leveraging virtualization technologies to consolidate network functions into general-purpose hardware platforms. On the past years extensive effort has been made to evolve and mature NFV tecnologies over IP networks ...
José Castillo Lema +3 more
openaire +2 more sources
Secure Fragmentation for Content-Centric Networks [PDF]
2015 IEEE 14th International Symposium on Network Computing and Applications, 2015 Content-Centric Networking (CCN) is a communication paradigm that emphasizes content distribution. Named-Data Networking (NDN) is an instantiation of CCN, a candidate Future Internet Architecture. NDN supports human-readable content naming and router-based content caching which lends itself to efficient, secure, and scalable content distribution ...
Cesar Ghali +4 more
openaire +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
IET Networks, 2020 Named data networking (NDN) corresponds to content‐centric networking, content‐based networking, and data‐oriented networking. Future internet architecture is modelled to overcome the fundamental limitations of the present internet protocol‐based ...
Ramachandira Moorthy Buvanesvari +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cache replacement strategy based on content value
Dianxin kexue, 2018 The cache replacement mechanism is one of the important research issues of the content center network.Considering the limited cache space,the reasonable replacement of the cache content becomes a key factor affecting the overall performance of the ...
Dan HUANG, Rongfang SONG
doaj +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source