Results 161 to 170 of about 29,584,200 (316)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Describing ZYN-Related Content on TikTok: Content Analysis. [PDF]

Nicotine Tob Res
Donaldson SI, La Capria K, DeJesus A, Ganz O, Delnevo CD, Allem JP.   +5 more
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Scalable Audio-Content Analysis

EURASIP Journal on Audio, Speech, and Music Processing, 2010
Hyoung-Gook Kim, Liming Chen, Chung-Hsien Wu, Malcolm Slaney, Bhiksha Raj, Paris Smaragdis   +5 more
doaj   +2 more sources

Text as Data: The Promise and Pitfalls of Automatic Content Analysis Methods for Political Texts

Political Analysis, 2013
Justin Grimmer, Brandon M Stewart
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Pro- and Antifluoride Use Messages on YouTube in Japan: Content Analysis. [PDF]

JMIR Form Res
Nagao HS, Okuhara T, Suzuki-Chiba H, Okada H, Kiuchi T.   +4 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Content analysis of food advertisements on Iran broadcasting television channels. [PDF]

J Family Med Prim Care
Mohammadzadeh Z, Movahhed T, Sanaee B, Salari M.   +3 more
europepmc   +1 more source

The most prominent problems of diabetes education in Iran: A qualitative content analysis

, 2021
Faridokht Yazdani, Parvaneh Abazari, Fariba Haghani, Bijan Iraj   +3 more
openalex   +1 more source