Results 201 to 210 of about 29,584,200 (316)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Quality and content analysis of syphilis-related short videos on Douyin (TikTok): A cross-sectional study. [PDF]

Digit Health
Yang J, Zhao K, Liu J.
europepmc   +1 more source

Understanding the effectiveness of public relations strategies used during consumer product recalls : a case study and content analysis examination of Mattel's 2007 recall strategy

, 2011
Leia I. Smith
openalex   +1 more source

Green process innovation, green product innovation, and corporate financial performance: A content analysis method

Journal of business research, 2019
Xuemei Xie, Jiage Huo, Hailiang Zou
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Moral disengagement in critical care nurses: a conventional content analysis. [PDF]

BMC Med Ethics
Khanipour-Kencha A, Jackson AC, Barati-Rizi S, Bahramnezhad F.   +3 more
europepmc   +1 more source

Limited consensus on what climate anxiety is: Insights from content overlap analysis on 12 questionnaires

Silke van Dijk, Kevin van Schie, Tom Smeets, Gaëtan Mertens   +3 more
openalex   +1 more source

Establishing geographically specific norms for a content-based analysis of spoken narratives in Spanish speakers

, 2018
Karla Simonet, Anthony Pak‐Hin Kong, Ashle Aguiar, Kassandra Capi, Betsali Cintron-Vargas, Erica Reynoso, Tamar Nir   +6 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Vaccination Conversations on X in Spanish and Catalan: Qualitative Content Analysis. [PDF]

JMIR Infodemiology
Huguet-Feixa A, Ahmed W, Artigues-Barberà E, Sol J, Godoy P, Ortega Bravo M.   +5 more
europepmc   +1 more source