Results 41 to 50 of about 74,356 (308)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Ontology of Gaps in Content-Based Image Retrieval [PDF]
Journal of Digital Imaging, 2008 Content-based image retrieval (CBIR) is a promising technology to enrich the core functionality of picture archiving and communication systems (PACS). CBIR has a potential for making a strong impact in diagnostics, research, and education. Research as reported in the scientific literature, however, has not made significant inroads as medical CBIR ...
Thomas Martin Deserno +2 more
openaire +2 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Content‐based image retrieval system via sparse representation
IET Computer Vision, 2016 The aim of image retrieval systems is to automatically assess, retrieve and represent relative images‐based user demand. However, the accuracy and speed of image retrieval are still an interesting topic of many researches.
Sajad Mohamadzadeh, Hassan Farsi
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interactive Content Based Image Retrieval using Multiuser Feedback
JOIV: International Journal on Informatics Visualization, 2017 Retrieving images from large databases becomes a difficult task. Content based image retrieval (CBIR) deals with retrieval of images based on their similarities in content (features) between the query image and the target image.
M. Premkumar, R. Sowmya
doaj +1 more source
Multiple layar kernel-based approach in relevance feedback content-based image retrieval system
, 2005 Relevance feedback has drawn intense interest from many researchers in the field of content-based image retrieval (CBIR). In recent years, kernel-based approach has been a popular choice for the implementation of the relevance feedback based CBIR system.
Chun-Che Fung +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
IEEE Access, 2022 With the rapid advancement of medical imaging technologies, the high-resolution CT image data is becoming increasingly valuable for both medical research and clinical diagnosis. The paper takes lung CT image as an example.
Yi Zhuang, Nan Jiang, Shuai Chen
doaj +1 more source