Results 81 to 90 of about 74,356 (308)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

From Content-Based Image Retrieval by Shape to Image Annotation

Advances in Electrical and Computer Engineering, 2010
In many areas such as commerce, medical investigations, and others, large collections of digital images are being created. Search operations inside these collections of images are usually based on low-level features of objects contained in an image ...
MOCANU, I.
doaj   +1 more source

Relevance feedback and intelligent technologies in content-based image retrieval system for medical applications

, 2004
Relevance feedback has gained much interest from researchers in the discipline of content-based image retrieval (CBIR). However, such approach is rarely used in the content-based medical image retrieval (CBMIR) systems.
Fung, C.C., Chung, K.P.
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Content Based Image Retrieval on Satellite Imagery

2023 31st Signal Processing and Communications Applications Conference (SIU), 2023
In this study, a content-based image retrieval system for satellite imagery is proposed. The main purpose of the paper is to find the most relevant images to the query image from a massive satellite imagery database using deep learning methodology. For this purpose, graph convolutional network and hash network are combined for image retrieval tasks ...
openaire   +2 more sources

Block-based Against Segmentation-based Texture Image Retrieval

, 2010
This paper concerns the best approach to the capture of local texture features for use in content-based image retrieval (CBIR) applications. From our previous work, two approaches have been suggested, the multiscale block-based approach and the automatic
Lewis, Paul, Fauzi, Mohammad Faizal Ahmad, Lewis,Paul, Fauzi,Mohammad Faizal Ahmad   +3 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Automated benchmarking in content-based image retrieval

IEEE International Conference on Multimedia and Expo, 2001. ICME 2001., 2001
Benchmarking has always been a crucial problem in content-based image retrieval (CBIR). A key issue is the lack of a common access method to retrieval systems, such as SQL for relational databases. The Multimedia Retrieval Mark-up Language (MRML) solves this problem by standardizing access to CBIR systems (CBIRSs).
Muller, Henning, Muller, Wolfgang, Marchand-Maillet, Stéphane, Squire, David, Pun, Thierry   +4 more
openaire   +4 more sources

Content-based image retrieval using a mobile device as a novel interface

, 2005
This paper presents an investigation into the use of a mobile device as a novel interface to a content-based image retrieval system. The initial development has been based on the concept of using the mobile device in an art gallery for mining data about ...
Hare, Jonathon S., Lewis, Paul H.
core