Results 191 to 200 of about 671,187 (212)

The Health and Physical Education Curriculum: Does It Address Muscular Fitness? [PDF]

J Funct Morphol Kinesiol
Sortwell A, Ramirez-Campillo R, Granacher U, Joyce C, Forte P, Marinho DA, Ferraz R, Trimble K.   +7 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Decoding the Avian Missing Gene Mystery: Dot Chromosomes Unmask Extensive Gene Loss and Novel Genetic Instability. [PDF]

Genome Biol Evol
Hron T, Miklík D, Pačes J, Pajer P, Pečenka V, Hejnar J, Nehyba J, Elleder D.   +7 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Development and content validation of an educational manual for promoting physical activity among older adults in India. [PDF]

Sci Rep
Mahatme S, Sinha MK, Ravindran SK, Amin R, Vaishali K.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Cosmetics and personal hygiene primary plastic packaging dataset: Characterization of post-consumer waste returned via take-back system in Denmark. [PDF]

Data Brief
Moscatelli G, Logan HM, Ipsen LD, Bisgaard JS, Astrup JHH, de Souza RG, Eriksen MK, Damgaard A.   +7 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Mobile Apps and Websites With Breastfeeding-Related Content in Germany: Cross-Sectional and Evaluation Study. [PDF]

JMIR Pediatr Parent
Ziebart M, Jäger V, Theurich MA, Koletzko BV.   +3 more
europepmc   +1 more source

Assessing content validity of learner milestones for decolonial global health education: A modified Delphi study. [PDF]

PLOS Glob Public Health
Edwards JG, Russ CM, Alayande B, Dela Rosa JG, Dogar M, Fitzgerald TN, Gonzalez P, Irfan A, Olufadewa II, Rivera-Segarra E, Siegel E, Williams M, Ratner L.   +12 more
europepmc   +1 more source