Results 181 to 190 of about 1,230,989 (267)

Secure content management in authorised domains

, 2002
van den Heuvel, S.A.F.A., Jonker, W., Jonker, Willem, Kamperman, F.L.A.J., Lenoir, P.J.   +4 more
openaire   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Bio-inspired spatiotemporal cascade reaction liposome for ferroptosis treatment following subarachnoid hemorrhage. [PDF]

Mater Today Bio
Peng Z, Li XJ, Xi YL, Zhu XL, Lu Y, Zhou Y, Yan HY, Wang J, Yang ZM, Hang CH, Ding YN, Wang JL, Li W.   +12 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Active regulation of the epidermal growth factor receptor by the membrane bilayer. [PDF]

Elife
Srinivasan S, Lin X, Chen X, Regmi R, Zhang B, Schlau-Cohen GS.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Development and Pilot Validation of an Age-Friendly City Assessment Tool Based on Older Adults' Perspectives in a Semi-Urban Community. [PDF]

Int J Environ Res Public Health
Punyakaew A, Karakate P, Nukeaw T, Saopasee T, Putthinoi S.   +4 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Physiological and transcriptomic analyses for assessing the effects of uniconazole on female ear development in maize (Zea Mays L.). [PDF]

BMC Plant Biol
Xu L, Wang H, Wang X, Zhang J, Jei V, Cheng D, Zhao Y.   +6 more
europepmc   +1 more source