Results 71 to 80 of about 1,231,912 (310)

SharePoint as enabler for collaboration and efficient project knowledge sharing

open access: yesSouth African Journal of Information Management, 2019
Background: Cutting-edge web technology applications have improved the manner in which business is conducted, allowing organisations to deliver business projects effectively. There is an untapped potential to power up SharePoint as a business application
Sithembiso Khumalo, Martie Mearns
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Roundtable: How do you like to do professional development?

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research, 2018
For this issue, we asked readers how they prefer their pro-dev: face-to-face, online, conferences, journal clubs, or something else? As you can imagine, the answers indicate a little of everything. Enjoy!
Karen Tiveron, Stephanie Savage
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

HoloGaussian Digital Twin: Reconstructing 3D Scenes with Gaussian Splatting for Tabletop Hologram Visualization of Real Environments

open access: yesRemote Sensing
Several studies have explored the use of hologram technology in architecture and urban design, demonstrating its feasibility. Holograms can represent 3D spatial data and offer an immersive experience, potentially replacing traditional methods such as ...
Tam Le Phuc Do   +5 more
doaj   +1 more source

Web Content Management Systems, a Collaborative Environment in the Information Society [PDF]

open access: yesInformatică economică, 2009
The aim of the present paper is to analyze the main models of collaboration and the use of a Web CMS, in order to develop an online community.
Daniel MICAN   +2 more
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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