Results 71 to 80 of about 1,231,912 (310)
SharePoint as enabler for collaboration and efficient project knowledge sharing
Background: Cutting-edge web technology applications have improved the manner in which business is conducted, allowing organisations to deliver business projects effectively. There is an untapped potential to power up SharePoint as a business application
Sithembiso Khumalo, Martie Mearns
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Roundtable: How do you like to do professional development?
For this issue, we asked readers how they prefer their pro-dev: face-to-face, online, conferences, journal clubs, or something else? As you can imagine, the answers indicate a little of everything. Enjoy!
Karen Tiveron, Stephanie Savage
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Several studies have explored the use of hologram technology in architecture and urban design, demonstrating its feasibility. Holograms can represent 3D spatial data and offer an immersive experience, potentially replacing traditional methods such as ...
Tam Le Phuc Do +5 more
doaj +1 more source
Web Content Management Systems, a Collaborative Environment in the Information Society [PDF]
The aim of the present paper is to analyze the main models of collaboration and the use of a Web CMS, in order to develop an online community.
Daniel MICAN +2 more
doaj
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source

