FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Facebook Doesn't Like Sexual Health or Sexual Pleasure: Big Tech's Ambiguous Content Moderation Policies and Their Impact on the Sexual and Reproductive Health of the Youth. [PDF]
Int J Sex Health, 2021 Borrás Pérez P.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Applying Net neutrality rules to social media content moderation systems [PDF]
, 2022 Winston Maxwell
openalex
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Enhancing digital resilience through GEN-AI driven video content moderation and copyright protection
International Journal of Applied Mathematics, Sciences, and Technology for National DefenseIn the digital era, ensuring digital resilience in video content moderation and copyright enforcement is crucial due to the vast volume of uploads. Traditional manual review methods are inefficient, necessitating AI-driven automation. This paper presents
Muthumanickam K +3 more
doaj +1 more source
Building and Executing MOOCs: A Practical Review of Glasgow's First Two MOOCs (Massive Open Online Courses) [PDF]
, 2015 No abstract ...
Houston, Suzy +3 more
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Guidance on the self-assessment of a provider’s financial management and control arrangements using the financial management and control evaluation (FMCE) return: version 2, november 2010 [PDF]
, 2010 This guidance has been prepared for the providers that the Skills Funding Agency takes the “lead” for on assurance matters. However, it is also equally applicable to those providers that the YPLA directly funds and l takes the “lead” for on assurance ...
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