Results 61 to 70 of about 5,507,675 (301)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Short-Term Time-Varying Request Model Based Chunk Caching Scheme for Live Streaming in Mobile Edge-Cloud Environment

open access: yesIEEE Access, 2019
Mobile Edge Computing Caching System (MECCS) realizes low-latency and high-bandwidth content access and enables seamless 4K Ultra High Definition (UHD) video streaming by caching content in advance at edge-servers of a cellular network.
Woo-Joong Kim   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Behavior Variations and Their Implications for Popularity Promotions: From Elites to Mass on Weibo

open access: yesEntropy, 2022
The boom in social media with regard to producing and consuming information simultaneously implies the crucial role of online user influence in determining content popularity.
Bowen Shi, Ke Xu, Jichang Zhao
doaj   +1 more source

Online Learning Models for Content Popularity Prediction in Wireless Edge Caching [PDF]

open access: yesAsilomar Conference on Signals, Systems and Computers, 2019
In the geographical edge caching, where base stations (BSs) and users are distributed as Poisson point process (PPP) and the caching performance is measured using average success probability (ASP), we consider the content popularity (CP) prediction ...
N. Garg   +4 more
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Survey on Content Placement Algorithms for Cloud-Based Content Delivery Networks

open access: yesIEEE Access, 2018
This paper provides a comprehensive survey of content placement (CP) algorithms for cloud-based content delivery networks (CCDNs). CP algorithms are essential for content delivery for their major role in selecting content to be stored in the ...
Mohammad A. Salahuddin   +4 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Movie Popularity and Target Audience Prediction Using the Content-Based Recommender System

open access: yesIEEE Access, 2022
The movie is one of the integral components of our everyday entertainment. The worldwide movie industry is one of the most growing and significant industries and seizing the attention of people of all ages.
Sandipan Sahu   +5 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

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