Results 161 to 170 of about 13,388,209 (287)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

AI teaching innovation behavior among college teachers: a structural equation modeling analysis based on the AI-TPACK framework, teaching self-efficacy, professional identity, and AI literacy. [PDF]

Front Psychol
Bai X, Hsieh TS.
europepmc   +1 more source

Understanding Gender: Methods, Content, andControversies

, 2013
Ryan, Michelle K., Branscombe, Nyla R.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development and Preliminary Evaluation of a Questionnaire on Parental Informed Consent in Neonatal Research. [PDF]

Children (Basel)
Lampridou M, Pouliakis A, Mougiou V, Katsianou E, Konstantinidi A, Theodoraki M, Iliodromiti Z, Boutsikou T, Iacovidou N, Sokou R.   +9 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Toward an integrated and globally equitable understanding of political polarization. [PDF]

Nat Commun
Falkenberg M, Cinelli M, Galeazzi A, Bail CA, Benito RM, Bruns A, Gruzd A, Lazer D, Lee JK, McCoy J, Nagayoshi K, Rand DG, Scala A, Siegel AA, van der Linden S, Varol O, Weber I, Wojcieszak M, Zollo F, Baronchelli A, Quattrociocchi W.   +20 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Medical students' perception of the role of nursing in medical care: implications for interprofessional education. [PDF]

Front Med (Lausanne)
Valerius L, Hagedorn J, Albert C, Wendler J, Werwick K, Braun-Dullaeus RC, Stieger P.   +6 more
europepmc   +1 more source

Understanding Creators' Acceptance of Content Reuse

Companion Publication of the 2024 Conference on Computer-Supported Cooperative Work and Social Computing
Riya Sinha, Hanlin Li 0001
openaire   +1 more source