Results 81 to 90 of about 10,237,477 (300)

Construction and validation of a matrix for normative evaluation of the integrated health system of the borders

Revista Latino-Americana de Enfermagem
Objective: to build and validate a matrix for normative evaluation of the Integrated Health System of Borders. Method: a methodological study, composed by the construction of an evaluation matrix elaborated in three stages: elaboration of the logical ...
Luciana Aparecida Fabriz, Valéria Conceição de Oliveira, Fabiana Costa Machado Zacharias, Silvia Helena Valente, Denise Ferro, Ione Carvalho Pinto   +5 more
doaj   +3 more sources

Bladder ultrasound: evidence of content validity of a checklist for training nurses [PDF]

Objectives: to develop and analyze evidence of content validity of a checklist for training nurses in measuring bladder volume through ultrasound.
Vinícius Batista Santos, Flávia Manfredi Cavalcanti, Beatriz Murata Murakami, Dejanira Aparecida Regagnin, Filipe Utuari de Andrade Coelho, Sabrina Martins Reigota   +5 more
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Content validity questionnaire

, 2020
Research: The Content Aspect of Validity in a Rubric-based Assessment Model of Course Syllabuses. Dataset description: Data from the optional field of the content validity questionnaire, and spreadsheet with the data and calculations ...
Menéndez-Varela, José-Luis
core   +1 more source

Table_1_A review of Lawshe’s method for calculating content validity in the social sciences.docx

, 2023
This study aimed to show the usefulness of Lawshe’s method (1975) in investigating the content validity of measurement instruments under the strategy of expert judgment.
Tarik Faouzi Nadim (17415381), Marcela Romero Jeldres (17415375), Elisabet Díaz Costa (17415378)   +2 more
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Validating a theory of planned behavior questionnaire for assessing changes in professional behaviors of medical students

Frontiers in Medicine
IntroductionTeaching professionalism is a fundamental aspect of medical undergraduate education, delivering important domains of professional attitudes, ethics, and behaviors.
Shaista Salman Guraya, Eric Clarke, Asil Sadeq, Mary Smith, Sinead Hand, Frank Doyle, Grainne Kearney, Mark Harbinson, Aine Ryan, Fiona Boland, Abdelsalam Bensaaud, Salman Yousuf Guraya, Denis W. Harkin   +12 more
doaj   +1 more source