Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms
Advanced Functional Materials, EarlyView.Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger +5 more
wiley +1 more source
Natural Si/N Co-Doped Porous Biomass Carbon Micron-Tubes as High-Performance Anode Materials for Lithium-Ion Batteries. [PDF]
Materials (Basel)Xu Z, Cao K, Wang Z.
europepmc +1 more source
Self‐Adaptive Gradient Interphase Enables Durable Solid‐State Lithium Metal Batteries
Advanced Functional Materials, EarlyView.This work presents a machine learning‐guided interfacial design that forms a self‐adaptive graded interphase on lithium metal anode. A B105M40 composite interlayer evolves into lithiophilic, porous, and fast‐ion‐conducting phases, enabling intimate contact, dendrite suppression, and uniform lithium deposition.
Hongmin Liu +9 more
wiley +1 more source
Multifarious approaches of implementation to transfer gender sensitivity in health care practice: a scoping review. [PDF]
BMC Health Serv ResMollenhauer J +5 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Bioinspired Bouligand architectures are translated into biodegradable polymer laminates with integrated sensing, revealing how structural design governs multifunctional performance. A 20° interlayer rotation optimizes strength, flexibility, and electromechanical response, while embedded nanotube networks enable real‐time damage detection and wearable ...
Piotr K. Szewczyk +4 more
wiley +1 more source
Protocol for a randomized trial to predict the efficacy of cognitive and behavioral interventions for symptoms of depression. [PDF]
Front PsychiatryDing J +7 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
Comparative analysis of machine-learning methods for prediction of pilot performance during startle events from neuropsychophysiological features of stress resilience and cognitive task scores. [PDF]
Front PhysiolGambiraža M +3 more
europepmc +1 more source