Results 91 to 100 of about 1,107,060 (390)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The Critical Assessment of Small Molecule Identification (CASMI): Challenges and Solutions
Metabolites, 2013 The Critical Assessment of Small Molecule Identification, or CASMI, contest was founded in 2012 to provide scientists with a common open dataset to evaluate their identification methods.
Steffen Neumann, Emma L. Schymanski
doaj +1 more source
The beauty of "bigness" in contest design: merging or splitting? [PDF]
This paper studies in a multiple-winner contest setting how the total efforts may vary between a grand contest and a set of subcontests. We first show that the rent-dissipation rate increases when the numbers of contestants and prizes are "scaled up". In
Fu, Qiang, Lu, Jingfeng
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
The Equivalence of Contests [PDF]
We use a Tullock-type contest model to show that intuitively and structurally different contests can be strategically and revenue equivalent to each other. We consider a two-player contest, where outcome-contingent payoffs are linear functions of prizes,
Roman M. Sheremeta +1 more
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Physical Culture and Sport: Studies and Research, 2019 Loy and Morford focus on “agon” as an important window through which to understand human life and development. Competition in war and sport was culturally significant then, and it is culturally significant today, albeit in modified forms.
Kretchmar R. Scott
doaj +1 more source
Anodal tDCS Over the Right Temporoparietal Junction Lowers Overbidding in Contests
Frontiers in Neuroscience, 2019 Overbidding, which means bidding over the Nash equilibrium, is commonly observed in competitive social interactions, such as a contest or auction. Recent neuroscience studies show that the right temporoparietal junction (rTPJ) is related to overbidding ...
Minda Wang +6 more
doaj +1 more source
, 2019 Polycentricity implies the diffusion of sovereignty over several levels of governance and numerous institutions. It envisages an explicit role for non-governmental bodies, such as private and community-based organisations and it puts the individual at the heart of society and social construction.
openaire +1 more source