Results 51 to 60 of about 859,079 (303)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Language Representation Models: An Overview
In the last few decades, text mining has been used to extract knowledge from free texts. Applying neural networks and deep learning to natural language processing (NLP) tasks has led to many accomplishments for real-world language problems over the years.
Thorben Schomacker +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Inductive Synthesis of Cover-Grammars with the Help of Ant Colony Optimization
A cover-grammar of a finite language is a context-free grammar that accepts all words in the language and possibly other words that are longer than any word in the language.
Wieczorek Wojciech
doaj +1 more source
On regularity of context-free languages
This paper considers conditions under which a context-free language is regular and conditions which imposed on (productions of) a rewriting system generating a context-free language will guarantee that the generated language is regular. In particular: (1) necessary and sufficient conditions on productions of a unitary grammar are given that guarantee ...
Andrzej Ehrenfeucht +2 more
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Seeker:Flow-sensitive Demand-driven Points-to Analysis [PDF]
Many demand-driven points-to analysis techniques are proposed to suit some environments bounded by strict limits of time and memory usage.Improving the demand-driven points-to analysis in a flow sensitive manner helps achieve precise points-to relations ...
XIAO Kejun,YU Haibo,CHEN Yuting,ZHONG Hao
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Implicit learning of recursive context-free grammars.
Context-free grammars are fundamental for the description of linguistic syntax. However, most artificial grammar learning experiments have explored learning of simpler finite-state grammars, while studies exploring context-free grammars have not assessed
Martin Rohrmeier +2 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

